A&E | 9:00 pm

Based in a party town so notorious it's nicknamed Sin City, Season 22 of this acclaimed docuseries opens an all-new seven episode season in Las Vegas with a two-hour premiere episode. That opening episode alone features some of the most harrowing drug addiction crises ever chronicled on this series, but over the course of these new episodes, viewers will get a "big picture" take on how Vegas has been affected by the devastating wave of addiction that has been plaguing America as a whole.